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(Download) "Resistance to Molecular Therapies for Hepatocellular Carcinoma" by Augusto Villanueva * eBook PDF Kindle ePub Free

Resistance to Molecular Therapies for Hepatocellular Carcinoma

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eBook details

  • Title: Resistance to Molecular Therapies for Hepatocellular Carcinoma
  • Author : Augusto Villanueva
  • Release Date : January 14, 2017
  • Genre: Medical,Books,Professional & Technical,
  • Pages : * pages
  • Size : 2179 KB

Description

This volume evaluates the clinical patterns of resistance to sorafenib, the impact of trial design in the second-line setting and the current gold standard to define radiological resistance; describes the molecular mechanisms responsible for treatment resistance in HCC patients, including components of the immune system and tumor microenvironment; determines the role of the cancer stem cell phenotype in resistance; reviews the experimental models to study resistance; and addresses new approaches to overcome resistance to sorafenib, using successful examples from other malignancies.


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